Top 75 Clinical Trial Patient Recruitment Companies & Tech Solutions (2025 Mega List)
Clinical trial timelines still break on one thing: patients. Recruitment delays drive 80% of trial extensions and burn millions in budget. Yet, 2025 finally feels different. A new wave of data-driven outreach, AI-powered feasibility, and decentralized engagement tools is cutting screen failure rates and accelerating first-patient-in. If you’re a CRA, CRC, or Clinical Project Manager trying to scale enrollment, this mega list shows the categories, vendors, and tech patterns worth knowing now.
While you explore, deepen your strategic edge with risk management frameworks, learn clinical trial budget oversight, and master GCP documentation standards—so your enrollment narrative impresses sponsors and auditors alike.
Why recruitment has shifted in 2025
Old-school physician referral networks and static IRB ads can’t fill complex oncology or rare disease studies fast enough. Modern recruitment is now multi-channel and data-driven:
Real-world data (RWD) & EHR mining: Platforms query structured EHR, claims, and genomic data to spot matches.
AI pre-screening: Natural language tools parse charts to auto-flag eligible subjects.
Digital outreach: Social, search, and patient community partnerships generate consent-ready leads.
Decentralized trial support: Tools integrate telehealth, eConsent, and home health visits to remove location barriers.
To play at this level, you need tech that’s HIPAA/GDPR compliant, integrates with CTMS/EDC, and proves ALCOA+ evidence—concepts you’ll find in GCP mastery and documentation best practices.
| Company / Platform | Specialty / Recruitment Strength | Pair With (CCRPS skill) |
|---|---|---|
| Acurian Health (PPD/Thermo Fisher) | Mass outreach Centralized media + pre-screen call centers. | Budget oversight |
| Antidote | Patient matching Performance digital + structured pre-screen. | GCP mastery |
| TrialSpark | Tech-enabled sites Onboards community clinics as research hubs. | PM techniques |
| SubjectWell | Pay-per-randomized Large global patient marketplace; pay on outcomes. | Risk frameworks |
| Deep 6 AI | EHR NLP Unstructured + structured EHR mining for eligibility. | Chart review skills |
| Clario (formerly ERT) | eCOA & engagement ePRO/eDiary improving adherence and retention. | Data discipline |
| Science 37 | DCT Metasite model + telehealth nurses for reach & retention. | DCT trends |
| Medable | DCT platform Global eConsent, remote visits, patient recruitment tools. | Global reach |
| Innovo Research | Physician network Primary-care network + EHR matching to protocols. | Documentation rigor |
| Elligo Health Research | Healthcare-enabled research Turns clinics into sites; real-world patients. | Site enablement |
| Clariness (ClinLife) | Global recruiting Multilingual portals + country-level media ops. | Global reach |
| Citeline Connect | Referral hub Central patient referral + site lead routing (Citeline). | PM techniques |
| Trialbee | Identity-resolved Audience segmentation + patient-centric pre-screens. | Data discipline |
| Massive Bio | Oncology matching AI-led matching + nav team for rare cancers. | Chart review skills |
| TriNetX | Global EHR network Cohort discovery + feasibility + site identification. | Data discipline |
| Flatiron Health | Oncology EHR Real-world data + disease registries for feasibility. | Documentation rigor |
| Tempus | Molecular + EHR Genomic-driven matching; precision oncology cohorts. | Risk frameworks |
| ConcertAI | RWD oncology AI cohorts + tokenized data for site targeting. | Data discipline |
| IQVIA Patient Recruitment | Full-stack Media, call center, EHR/claims targeting at scale. | Budget oversight |
| Walgreens Clinical Trials | Retail reach Pharmacy reach, diverse neighborhoods, in-store touchpoints. | Global reach |
| Circuit Clinical | Community trials Health-system + community-based site network. | Site enablement |
| Care Access | Mobile sites Pop-up/mobile sites to reach under-served populations. | Risk frameworks |
| THREAD | DCT platform eConsent, ePRO, telehealth with recruitment add-ons. | DCT trends |
| Castor | eConsent/ePRO Rapid eConsent + digital pre-screens to lift conversion. | Documentation rigor |
| uMotif | Patient UX Engagement app reduces drop-off, improves diary compliance. | Data discipline |
| Evidation | Consumer data → trials Identifies phenotypes & recruits from a large panel. | Chart review skills |
| BBK Worldwide | Global campaigns Multichannel patient recruitment & retention since 1980s. | Budget oversight |
| WCG Patient Engagement | IRB + engagement Education, outreach, pre-screen call handling integrated with IRB. | GCP mastery |
| StudyKIK (by SubjectWell) | Community High-intent patient communities + pre-screen routing. | PM techniques |
| Power (WithPower) | Marketplace Self-serve patient discovery + site matching tools. | Risk frameworks |
| ClinicalConnection | Study listing Condition-targeted study directories with opt-in alerts. | Documentation rigor |
| ResearchMatch (Vanderbilt) | Academic registry Volunteer registry used by 200+ institutions (US). | GCP mastery |
| CISCRP | Education & awareness Patient-friendly materials + community outreach events. | Documentation rigor |
| Inspire | Patient communities 2,000+ condition groups; compliant outreach opportunities. | Risk frameworks |
| HealthUnlocked | Communities Global health forums; advocacy partnerships for trials content. | Chart review skills |
| Rare Patient Voice | Rare disease panel Hard-to-reach patients/caregivers for feasibility & referral. | Global reach |
| Komodo Health | Claims + RWE Tokenized patient journeys for cohort discovery & geo-targeting. | Data discipline |
| HealthVerity | Identity resolution Real-world data linkage to identify eligible populations securely. | Data discipline |
| Phreesia Life Sciences | Point-of-care EHR check-in screens; condition-matched trial messages. | PM techniques |
| Doximity | HCP network Physician targeting for referrals to nearby sites/studies. | Budget oversight |
| Sermo | HCP referrals Panel & messaging to drive specialist referrals to sites. | Documentation rigor |
| TrialJectory | Oncology AI matching Patient-entered data → algorithmic study fit + nav team. | GCP mastery |
| Greenphire | Payments & travel ClinCard + travel simplifies participation & reduces drop-outs. | Budget oversight |
| Clincierge | Concierge travel Door-to-door logistics (visas, lodging) for global trials. | Risk frameworks |
| Uber Health | Transport HIPAA-aligned ride coordination for visit adherence. | Site enablement |
| Lyft Healthcare | Transport Non-emergency medical transport to reduce visit no-shows. | Risk frameworks |
| LanguageLine Solutions | Interpreting On-demand interpreters for screening & consent conversations. | Documentation rigor |
| TransPerfect Life Sciences | Translation Patient-facing materials & eCOA localization for retention. | GCP mastery |
| Advarra | IRB + tech Central IRB plus participant portal & eConsent ecosystem. | Documentation rigor |
| Florence Healthcare | eBinders/site enablement Faster start-up → earlier recruiting at sites. | Site enablement |
| OneStudyTeam (Reify Health) | Lead mgmt Centralized lead routing, pre-screen tracking across sites. | Data discipline |
| Veeva SiteVault | Site start-up Streamlined regulatory to pull-forward FPFV & recruitment. | PM techniques |
| Playbook: Facebook Lead Ads | Digital HIPAA-safe flows via lead forms + site-level call follow-up SLAs. | Budget oversight |
| Playbook: Google Search (High-intent) | Digital Keyword clusters by symptom/diagnosis + geo to site catchments. | Risk frameworks |
| Playbook: YouTube Pre-roll | Awareness 6–15s bumpers to lift branded search & referral volume. | GCP mastery |
| Playbook: Reddit Ads | Communities Condition subreddits with strict comment policy + FAQ landing pages. | Chart review skills |
| Playbook: TikTok Awareness | Short video Compliance-approved narratives to improve trust & literacy pre-screen. | Global reach |
| Playbook: Patient Portal Messaging | EHR portal MyChart/portal messaging to identified cohorts with opt-in paths. | Data discipline |
| Playbook: HIPAA-Compliant SMS | Re-engagement Time-boxed SMS cadence for warm leads; opt-in + audit trails. | Documentation rigor |
| Playbook: Community Health Workers | Trust CHWs embedded in clinics/churches/mosques to surface candidates. | Risk frameworks |
| Playbook: Faith-based Partnerships | Equity Co-created events in under-represented communities; referral loops. | GCP mastery |
| Playbook: Employer Coalitions | Population access Partner HR for chronic condition cohorts & flexible visit times. | PM techniques |
| Playbook: Independent Pharmacies | Point-of-care Counter cards/QR near therapies + pharmacist referral scripts. | Budget oversight |
| Playbook: Urgent Care Networks | Acute funnels Screen post-visit patients for study eligibility within 48h discharge. | Risk frameworks |
| Playbook: Telehealth Platforms | Virtual intake Warm handoffs from telemedicine visits into eConsent pipelines. | DCT trends |
| Playbook: Local Radio & Newspapers | Trust media Senior/immigrant segments; tracked via unique phone numbers. | Global reach |
| Playbook: Multilingual Landing Pages | Conversion Plain-language copy + dynamic phone routing by language/ZIP. | Documentation rigor |
| Playbook: Travel Reimbursement Policy | Retention Transparent stipend tiers; prepaid options to remove friction. | Budget oversight |
| Playbook: DEI Site Selection | Equity Choose sites with diverse catchments; monitor enrollment mix monthly. | Risk frameworks |
| Playbook: Patient Advisory Boards | Co-design Validate ads/scripts; iterate on barriers before launch. | Chart review skills |
| Playbook: KPI Dashboard | Ops Screen-fail%, randomization rate, cost/Rand, lead→visit SLA visualization. | Data discipline |
| Playbook: Standardized Pre-screen Script | Quality Readability ≤8th grade; adverse language scrub; objections map. | Documentation rigor |
| Playbook: Staff Referral Rewards | Internal Compliance-approved bonus for staff-referred randomized patients. | GCP mastery |
| Playbook: PCP Fax/EHR Letters | HCP referral One-page MD letter with inclusion bullets + site contact sheet. | PM techniques |
| Playbook: Pharmacy Bag Stuffers | Point-of-care RX-aligned education with IRB approval + QR to pre-screen. | GCP mastery |
| Playbook: Community Fairs | Grassroots Blood-pressure/diabetes screenings co-branded with study info. | Risk frameworks |
| Playbook: Local Influencers | How to use this mega listStep 1 — Map your trial profile. Step 2 — Pair tools with SOPs. Step 3 — Embed GCP-proofing. What’s your biggest patient recruitment barrier?Advanced playbook for 2025 recruiters
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