Top 100 Clinical Research Organizations (CROs) Hiring CRCs & CRAs in the USA (Complete 2025 Directory)
If you’re chasing your next CRC/CRA role, this is your market map—a U.S.-focused list of 100 CROs that routinely staff clinical operations teams across phases and therapeutic areas. You’ll see full-service giants and high-growth niche players—plus quick filters on services and the right link to jump straight to their careers page. Use this side by side with GCP mastery, exam prep, and salary intel from CCRPS to accelerate interviews and offers from day one (GCP guidelines mastery, GCP exam guide, CRA salaries 2025, CRC study guide).
How we picked and how to shortlist (fast)
The U.S. remains a powerhouse for CRO activity, with enterprise players (IQVIA, ICON, Thermo Fisher Clinical Research/PPD, Parexel, Medpace, Fortrea, Syneos) scaling study ops nationwide, while specialized CROs (oncology, device, early phase, rare disease) aggressively hire CRCs/CRAs for regional coverage. We triangulated 2025 U.S. CRO directories and industry lists plus revenue/market snapshots to ensure breadth and recency, then prioritized those with active U.S. presence + clear ops functions. For speed, first hit: full-service global CROs → mid-market specialists → early-phase labs with monitoring → device/regulatory hybrids (NAMSA/SGS) → emerging tech-enabled CROs. For every outreach sprint, sharpen your profile with project planning, risk management, and budget oversight keywords recruiters scan for (PM techniques, risk frameworks, budget oversight, protocol documentation).
Macro backdrop: CROs continue to expand through M&A and FSP models, keeping demand high for monitors and coordinators—a dynamic you can exploit in 2025 job searches. Proclinical+1
| CRO (U.S. Presence) | Core Services / Notes | Careers |
|---|---|---|
| IQVIA | Full-serviceFSPDecentralized Enterprise scale across all TAs; U.S. monitoring hubs. | jobs.iqvia.com |
| ICON plc (incl. legacy PRA) | Full-serviceFSP Phase I–IV; strong oncology & rare disease depth. | careers.iconplc.com |
| Parexel | Full-serviceHybrid/Remote Site start-up, monitoring, biostats, med writing; Triangle base. | jobs.parexel.com |
| Thermo Fisher Clinical Research (PPD) | Full-serviceLabs Former PPD; deep global FSP, biometric services. | Thermo Fisher → PPD |
| Medpace | Full-serviceCentral Labs Integrated labs; program leadership heavy. | medpace.com/careers |
| Fortrea | Full-serviceFSP Spin-out from Labcorp Drug Dev; strong U.S. CRA hiring. | careers.fortrea.com |
| Syneos Health | Full-serviceCommercial FSP and full-service CRAs across multiple TAs. | syneoshealth.com/careers |
| PSI CRO | GlobalOncology Reputation for high-quality monitoring & site relationships. | psi-cro.com/careers |
| Worldwide Clinical Trials | Phase II–IVCNS/Oncology High ISR benchmarking; U.S. CRA growth. | worldwide.com/careers |
| Premier Research | Rare diseaseMed Device Flexible FSP & full-service models. | premier-research.com/careers |
| Allucent (ex-Pharm-Olam) | BiotechGlobal SMB biotech focus; U.S. remote CRAs. | allucent.com/careers |
| Caidya (Clinipace + dMed) | Full-serviceOncology Global footprint; U.S. study ops hiring. | caidya.com/careers |
| Veristat | BiostatsOncology Biometrics-heavy trials; flexible U.S. remote roles. | veristat.com/careers |
| Emmes | Public healthBiometrics NIH/agency partnerships; monitoring & data roles. | emmes.com/careers |
| CTI Clinical Trial & Consulting | Rare diseaseCell/Gene U.S. & global CRA teams. | ctifacts.com/careers |
| Precision for Medicine | BiomarkersOncology Translational + clinical; monitoring ops nationwide. | precisionformedicine.com/careers |
| Rho | Full-serviceGov’t Noted for federal/NIH work; strong PM/CRA hiring. | rhoworld.com/careers |
| Celerion | Early PhasePK/PD U.S. clinical pharmacology units; coordinator roles. | celerion.com/careers |
| Charles River Laboratories | Preclinical→ClinicalLabs U.S. early phase & support services. | jobs.criver.com |
| QPS | Early phaseBioanalysis U.S. sites; CRA/CTA opportunities by study. | qps.com/careers |
| NAMSA | Medical deviceRegulatory U.S. device trials; CRC/CRA device pathways. | namsa.com/careers |
| SGS Clinical | Device/DrugLabs Mix of clinical ops + lab support; U.S. hubs. | sgs.com/careers |
| Novotech (U.S. presence) | APAC leaderOncology U.S. client ops; remote monitoring. | novotech-cro.com/careers |
| TFS HealthScience | Mid-marketFSP U.S. CRAs across specialty TAs. | tfscro.com/careers |
| CROMSOURCE | Full-serviceResourcing U.S. remote CRA teams. | cromsource.com/careers |
| ClinChoice | Full-serviceFSP Growing U.S. footprint; monitoring roles. | clinchoice.com/careers |
| Frontage Clinical | Early phaseBioanalytical U.S. units with CRC/CTA hiring. | frontagelab.com/careers |
| InClin | Bay AreaBiotech Full-service support; U.S. monitoring talent. | inclinfoundation.com/careers |
| Atlantic Research Group (ARG) | RareOncology U.S. CRAs for biotech studies. | atlanticresearchgroup.com/careers |
| Lotus Clinical Research | AnalgesiaHospital-based U.S. coordinating center roles. | lotuscr.com/careers |
| Catalyst Clinical Research | FSPOncology U.S. remote monitors & CTAs. | catalystcr.com/careers |
| Pivotal | OncologyEU→US U.S. expansion with CRA needs. | pivotalcr.com/careers |
| KCR | Mid-marketGlobal U.S. monitoring teams; biotech focus. | careers.kcrcro.com |
| ClinAccel (Accel Clinical) | SMBMulti-TA U.S. CRA/CRC postings by program. | LinkedIn Jobs |
| Vial | Tech-enabledFSP U.S. remote CRAs; startup biotech focus. | vial.com/careers |
| Theradex | OncologyRegulatory U.S. NCI heritage; CRA/CTA hiring. | theradex.com/careers |
| PRA Health Sciences (now ICON) | MergedLegacy teams U.S. roles route via ICON. | careers.iconplc.com |
| Synteract (now Syneos) | MergedFSP U.S. roles route via Syneos. | syneoshealth.com/careers |
| WuXi Clinical (U.S. presence) | GlobalBiometrics Multiregional studies; U.S. ops teams. | wuxiapptec.com/careers |
| Pharmaron | Early→LateLabs U.S. clinical ops growth. | pharmaron.com/careers |
| Tigermed (U.S. presence) | GlobalBiotech U.S. FSP roles by program. | tigermedgrp.com/career |
| PPD Biotech (Thermo Fisher) | SMB biotechFSP U.S. CRAs in startup programs. | jobs.thermofisher.com |
| Q2 Solutions (IQVIA) * | Central LabseBio *Lab partner—often co-hires with CRA programs. | jobs.iqvia.com |
| Clinscience | BiometricsFSP U.S. biometrics + monitoring support. | clinscience.com/careers |
| KCRN Research | SMBMulti-TA U.S. CRA/CRC roles; regional coverage. | kcrnresearch.com/careers |
| Medelis | OncologyGlobal Boutique oncology CRO; monitors by TA. | medelis.com/careers |
| Novella (IQVIA Biotech) | BiotechFSP U.S. CRA roles under IQVIA Biotech group. | jobs.iqvia.com |
| Cytel (Services) | BiostatsAdaptive Ops + data roles supporting U.S. trials. | cytel.com/careers |
| PRACTICAL (device/medtech) | DevicePMCF U.S. device studies; CRA/CTA hiring cycles. | practical-research.com |
| Biopharma Services USA | Early phaseBA/BE CRC/CTA roles at clinical units. | biopharmaservices.com/careers |
| PRAZ Clinical | SMBMulti-TA Regional U.S. monitoring. | prazclinical.com/careers |
| Caidian Research | SMBFSP U.S. CRA placements. | — |
How to turn this list into 3–5 interviews (this month)
Start by stacking GCP mastery with exam-ready habits recruiters recognize: protocol literacy, deviation management, consent nuance, and SDV discipline (GCP essentials, protocol deviations, protocol development, documentation under GCP).
Optimize your resume for CRO ATS: embed keywords like risk-based monitoring, EDC cleaning, I/E criteria enforcement, visit window control, and issue-action-resolution logs. Pair that with data-driven study metrics: query turnaround times, percent SDV at FPFV/DBL, and per-site enrollment velocity. Use CCRPS’s exam strategy playbooks to sharpen test-taking and interview performance (CRA exam guide, Top 100 CRA Q&As, exam anxiety fixes, test-taking strategies).
Pipeline your outreach: hit enterprise CROs (high req volume) and mid-market oncology/device (faster approvals). Expect stronger volume in areas expanding capacity (see revenue ranks and U.S. backlogs). Straits Research
If you’re coming from research assistant roles, transition faster with data collection mastery + lit review fluency and career-specific salary targets (RA data collection, lit reviews, salary report 2025, top-paying jobs).
Smart geography & market timing
U.S. coastal hubs (Boston/Cambridge, RTP, Bay Area) and Midwest growth corridors (Cincinnati—Medpace; Columbus/Dayton; Chicago) post consistent CRA reqs, while global expansion (India/APAC) influences FSP hiring cycles and remote monitoring utilization; understanding that macro flow helps you time applications and accept hybrid or remote flexibility. Pair U.S. attempts with country trend literacy to sound fluent in sponsor strategy (India’s trial boom, countries winning trials 2025, Brexit impacts). Industry consolidation, FSP growth, and private equity activity around site networks increase CRO demand for coordinators and monitors tied to portfolio upticks. Proclinical
Deep-dive: skills CRO recruiters scan for (and how to show them in 7 days)
1) GCP muscle memory (ICH E6 R2/R3): quote exact clauses (e.g., ALCOA+ in source, essential docs per 8.x). Pair with a line about audit readiness—then back it up with CCRPS study material (GCP exam tips, GCP Q&As).
2) Risk-Based Monitoring (RBM): explain how you used KRIs, centralized monitoring, and remote SDV to detect signal drift; tie to protocol deviation prevention (risk management for PMs, managing deviations).
3) Start-up velocity: prove you can compress SSU timelines by partnering with sites on IRB/IEC submissions and ICF localization; show first-patient-in dates met and reg binder completeness (project planning, PI leadership).
4) Data quality & query closure: speak to eCRF edit checks, DCF turnarounds, and DBL readiness; anchor to biostat collaboration and PV handshakes (data collection for RAs, PV prep guide).
5) Career compounding: if you’re CRC → CRA, stack CCRPS CRA exam prep + mock interviews; if you’re CRA → CPM, use CCRPS PM study guides and exam Q&As (CRA prep, CRA Q&A 100, CRPM guide, PM exam Q&As).
Which CRO tier are you targeting first?
What’s changing in CRO hiring (so you can surf the wave)
FSP expansion & hybrid monitoring: Sponsors lean on FSP 360 and similar models for flexibility, which lifts CRA requisitions even when individual study starts are staggered. Hybrid and decentralized trials keep U.S. monitoring demand broad—even as global hubs scale. Cross-reading macro and company news (expansions, HQ moves) helps you time applications (e.g., Parexel’s Triangle footprint and U.S. relocations signal sustained hiring). Pair this with APAC growth trends to frame yourself as a globally aware candidate in interviews. Kent State Online+2Axios+2
Private equity in sites & services: Ongoing investment in site networks and CRO platforms fuels portfolio ramp, creating fresh openings for coordinators and monitors aligned to new trials. Reuters
Revenue momentum: Revenue snapshots across leading CROs point to continued resourcing in clinical operations—a tailwind for CRC/CRA pipelines into 2026. Straits Research
Action step: build a two-track pipeline—(1) enterprise CROs for req volume; (2) niche CROs where your TA experience makes you the obvious short-list. Lock in a weekly study cadence for GCP and exam prep while applying (GCP study tips, PV prep, MSL/monitor Qs, PI responsibilities).
FAQs (read this before you apply)
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Master monitor-ready skills: SDV/SDR workflows, risk-based monitoring basics, issue management (identify → action → resolution), and visit cadence (SQV/SIV/IMV/Close-out). Translate CRC wins into monitor language: “maintained <2-day query TAT,” “drove 95% on-time visit windows,” “cut screen failure rate by 12% by tightening I/E criteria checks.” Use CCRPS’s CRA exam prep and mock Q&As to drill weak spots (CRA prep guide, Top 100 CRA Q&As, proven study strategies, perfect study environment).
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CROs predominantly hire CRAs, CTAs, SSU specialists, Trial/Project Coordinators—but many also hire in-house clinical research coordinators or site support coordinators, especially in early-phase units and FSP programs. Title conventions vary; focus on skills and study metrics more than labels. Keep GCP and documentation competency front-and-center (GCP full guide, deviation strategies, PI protocol development).
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Oncology remains a magnet; cell/gene, CNS, metabolic, and infectious diseases continue to support U.S. portfolios. Device PMCF studies also sustain monitoring needs. Your salary leverage improves when you can demonstrate TA depth—pair that with 2025 comp data to negotiate (salary report 2025, PV salaries, CRC salary guide).
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Yes. Hybrid/remote monitoring anchored to regional travel remains common (and FSP demand keeps it healthy). Emphasize home-office readiness, secure source access workflows, and video-enabled site support experience. For momentum, scan CROs in APAC/EU that run U.S. studies and hire U.S.-based monitors (countries winning trials, Africa frontier, China outlook).
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Translate experience into site-facing execution and protocol governance. If you’re RA → CRC/CRA, highlight data integrity, query resolution, and patient-visit orchestration (RA essentials, RA data management). If you’re on the PI path, leverage leadership and protocol ownership into CPM aspirations over time (PI responsibilities, PI certification guide, PI exam Q&As).
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Arrive with 3 mini case studies: (1) Source reconstruction under ALCOA+; (2) Deviation triage with CAPA; (3) Consent re-consent after protocol amendment. Cap each with a measurable outcome. Sharpen with CCRPS’s GCP exam prep and expert tips (GCP exam guide, expert tips).
